Options of precision medicine in pediatric oncology: literature review

In the last 50 years there has been significant improvement in survival for children with cancer, achieved by implementation of cooperative clinical research trials that found an opportunity to standardize and control treatment childhood cancer. Combined modalities approaches, intensification chemotherapy regimens high-risk disease allow reach 70 % rate all cases. Yet is still a need improve outcomes decrease side effects anticancer groups unfavorable prognosis. The most promising point personification special focus on targeted drug therapies immunotherapy. We reviewed recent international advances unique options precision medicine pediatric cancers.